Ostarine MK-2866 - Masculinedevelopment

Ostarine (MK-2866): The Full User’s Guide (Update 2020!)

Ostarine, otherwise known as enobosarm or MK 2866, is one of the most popular SARMs on the market—and it isn’t hard to see why.

Within just a matter of a few weeks, you can experience god-like increases in strength, enhanced physical performance, and crazy euphoria.

Over the past few years, SARMs such as Ostarine, have been exploding in popularity, due to their strength, and minimal side effects.

Thanks to advancements in modern science, you can now take a few drops of clear liquid every morning, and experience all of the benefits of taking illegal steroids with almost none of the negative side effects [1].

This is the power of SARMs: increased strength, enhanced physical performance, and fat shredding like never before.

Today however, I’d like to focus on a particular SARM known as Ostarine, or MK 2866. It’s by far one of the best SARMs, and for good reason.

Today, we’re going to be exploring everything you need to know, from the MK2866 side effects, to dosages, and exactly how to take it.

So, strap in, get yourself a cup of coffee, and let’s get to it!


History of Ostarine

mk 2866

SARMs such as MK-2866 began development in the 1940’s, originally as a pharmaceutical drug meant to help cancer patients build muscle [2].

The idea was that by giving patients SARMs, doctors could prevent all kinds of nasty side effects such as muscle wasting and fatigue.

Funny enough, they worked… and they worked REALLY freaking well. They’re by far one of the best muscle building supplements out there.

The SARMs that we’re talking about though, didn’t undergo research development until the early 1990’s, after big pharma caught wind.

Once big pharmaceutical companies like Merck began doing research on SARMs, bodybuilders across the world began to take note [3].


MK 2866 For Bodybuilding

Although it was originally created to treat muscle-wasting in cancer patients, bodybuilders quickly caught on to its benefits.

MK 2866 was originally developed by Merck & Company, but it was quickly acquired by a smaller company called GTx Incorporated.

GTx Incorporated quickly began developing and researching MK 2866, and they soon realized how powerful it was as an anabolic agent [4].

After thousands of men quickly became aware of the benefits of taking Ostarine, there suddenly emerged a huge demand for the stuff.

As with anything that’s highly effective though, good old Daddy Government swooped in and has desperately been trying to make it illegal.

Thankfully, SARMs aren’t illegal… yet. There’s still plenty of SARMs for sale online, so if you plan on buying them, you’d better do it soon.


How Does Ostarine Work?

how does ostarine work

MK-2866, Testolone, Ligandrol,, and all SARMs as a whole for that matter, work by selectively activating your body’s androgen receptors [5].

This leads to an extremely powerful effect, which mimics steroids, but with none of the side effects that you’d get from taking actual steroids.

Due to the selective nature of SARMs, users can put on muscle very rapidly, with very few side effects, if any at all.

There are very few Ostarine side effects, because SARMs only bind to the “good” androgen receptors, and avoid most of the “bad ones” [6].

If you decided to take a a bunch of steroids, such as Testosterone Enanthate for example, you’d be activating your androgen receptors left and right.

Sure, this leads to great gains in strength, but it also leads to all of the steroid effects that everyone hates—tiny balls, bitch tits, and roid rage.


Mechanism of Action

With SARMs such as MK2866 however, because they SELECTIVELY activate certain androgen receptors, you’ll get all of the good with none of the bad.

In other words, with SARMs, you can literally build muscle and shred fat, FAST AS HELL, without any of the side effects of steroids.

Users who take MK2866 often report incredible gains in strength, with none of the nasty side effects that steroids would give them.

In fact, studies have shown that Ostarine has a high affinity for muscle and bone androgen receptors, which means that they specifically target bicep, tricep, and shoulder muscles, instead of organ tissues.

In layman’s terms, MK-2866 will cause your muscles to get bigger and your bones to get denser, without causing the common side effects of steroids.


Top Ostarine Benefits

ostarine mk 2866 benefits

Some of the benefits of Ostarine (MK-2866)

MK2866 is one of the most widely used SARMs, which thankfully means it’s also one of the most widely tested. There’s a ton of research on it.

Here are a few Ostarine benefits:

  1. Build Muscle
  2. Increase Strength
  3. Shred Fat
  4. Gain Mass
  5. Few Side Effects

In fact, not only will MK 2866 help you build muscle, but when you take an Ostarine dosage between 25mg-50mg/day, there’s few side effects.

Personally, I’ve taken steroids, prohormones, and SARMs before, and SARMs are my new favorite anabolic agent. They work extremely well.

Build MuscleBuild Muscle
Lose FatLose Fat
Low Side EffectsMedium Side Effects
Low AromatizationHigh Aromatization

MK-2866 is similar in strength to a low grade dosage of steroids, and while it’s not as strong as they are, it has about 1% of the side effects.


My Ostarine Results

Before I go any further, I want to show you my Ostarine results.

I experienced some incredible benefits when I was on MK 2866, I’m not gonna lie. The muscle I built, and fat I lost, was pretty astounding.

In just 90 days of my Ostarine cycle, I put on about 18 pounds of muscle, and lost 7 pounds of fat, while increasing strength.

You can read my full SARMs Before and After post, for the full details, dosages, and summary, but here’s a quick summary.

I got on a SARMs cycle, and took the following, each day:

  • Ostarine (25mg/day)
  • Ligandrol (10mg/day)
  • Cardarine (10mg/day)

I got my SARMs from Proven Peptides, which in my opinion, is the best place to get high quality, 100% pure SARMs online. I trust no one else.

I took these dosages for 90 days, and saw some incredible results. I gained 18 pounds of muscle, lost 7 pounds of fat, and doubled my PR’s.

Most of these results were due to the MK2866, in my opinion—Ostarine is great for strength, and is one of the best SARMs on the market.

The Ligandrol helped me stay “cut and dry” and lose fat. LGD-4033 is one of the best SARMs for shredding, and making your muscles look cut.

The Cardarine on the other hand, was taken for endurance. Studies have shown it can increase endurance by up to 246% in test subjects [7].

Overall, that SARMs cycle was awesome, and I will definitely be doing it again. Be sure to stay tuned and read my blog for more reports!


MK 2866 Side Effects

ostarine side effects

Now, I know what you’re thinking—how the hell are there no Ostarine side effects, if it’s so damn powerful? I thought the same thing, too.

Well, if you ask me, Ostarine is nothing short of a wonder drug. It’s by far one of the best muscle building supplements on the planet.

I’ve personally used it to put on 15+ pounds of lean muscle mass in just a few months, as have countless other men who read this blog.

That being said, there are some potential risks for side effects that should be mentioned. I didn’t experience any, but some guys do.

If you take a normal enobosarm dose, between 25mg and 50mg per day, you probably won’t experience any of these side effects (I didn’t).

Most scientists agree that Ostarine has almost no side effects, and the only time people encounter them are when they take far more than they should.


Clinical Research Studies

There’s been numerous studies done on the potential Ostarine side effects, and overall most researchers have concluded that it’s very safe.

I myself have taken MK2866 many times before, and have carefully monitored my testosterone and cholesterol levels while on cycle.

I personally didn’t experience any side effects on my MK-2866 cycle, even when I took a dosage as high as 50mg/day.

That being said, let’s take a look at some of the clinical research done so far, and see what it has to say about the side effects of Ostarine.


Help Combat Muscle Atrophy

According to numerous studies, Ostarine is responsible for rapid muscle gain, and has almost zero side effects when taken in normal doses.

In one study conducted by GTx Pharmaceuticals, researchers found that Ostarine was very well tolerated, with minimal side effects [8].

“GTx-024 treatment resulted in dose-dependent increases in total lean body mass that were statistically significant (P < 0.001, 3 mg vs. placebo) and clinically meaningful. There were also significant improvements in physical function (P = 0.013, 3 mg vs. placebo) and insulin resistance (P = 0.013, 3 mg vs. placebo). The incidence of adverse events was similar between treatment groups.”

“GTx-024 showed a dose-dependent improvement in total lean body mass and physical function and was well tolerated. GTx-024 may be useful in the prevention and/or treatment of muscle wasting associated with cancer and other chronic diseases.”

In other words, taking Ostarine led to a significant increase in total lean body mass and physical function when compared to placebo.

As if this wasn’t enough, it was also “very well tolerated” in the researchers’ own words, which means it had almost zero side effects.


Rapid Increase in Muscle Mass

The benefits don’t stop there, though. Research has shown us that MK 2866 can not only help users build muscle, but rapidly shred fat, as well.

In a study conducted by the Department of Medicine at Saint Agnes Hospital, researchers found that Ostarine has a ton of benefits [9].

“The newly developed nonsteroidal selective androgen receptor modulator Ostarine has demonstrated promising results in Phase I and II clinical trials, increasing total lean body mass, enhancing functional performance and decreasing total tissue percent fat. This selective androgen receptor modulator may have the ability to perform as a potent anabolic agent with minimal side effects on other organs (prostate and hair follicles), thus presenting a new strategy in managing cancer cachexia.”

They stated that Ostarine can help increase total lean body mass, enhance physical performance, and even help users shred fat.


No Adverse Effects on Cholesterol

One of the most common side effects of steroids is increased cholesterol, so many users wonder if SARMs will lead to a similar result.

Fortunately, according to studies, Ostarine doesn’t increase cholesterol like a normal steroid would. In fact, it actually decreases cholesterol [10].

“An additional Phase II study in muscle wasting associated with cancer cachexia began in 2008 as an early objective of clinical development. Ostarine also resulted in a dose-dependent decrease in LDL and HDL cholesterol levels, with the average LDL/HDL ratio for all doses remaining in the low cardiovascular risk category.”

Are you convinced that Ostarine is pretty much the best thing to ever hit the bodybuilding market since pre workouts? If not, then keep reading.

Enobosarm has an incredible host of benefits from lean muscle gain, to rapid fast loss, to lower cholesterol, higher bone density, and more.


Ostarine Doses & Cycles

guy lifting weights

Alright, now it’s time for the good part—your Ostarine dosage. Most research shows us that you can take up to 50mg/day and be safe.

That being said, if it’s your first cycle, I recommend you start off with just 25mg of MK 2866 each day. It’s better to be safe than sorry.

If you want to do a SARMs stack however, you can gain the benefits of Ostarine, plus a ton of benefits from other SARMs like Ligandrol.

Right now, I’m on a stack of Ostarine, Cardarine, and Ligandrol. I’m taking all three of these SARMs daily, and I feel absolutely incredible.

The Ostarine is great for strength, the Ligandrol is great for fat loss, and the Cardarine? Well, let’s just say it JACKS UP your endurance like crazy.


Best Ostarine Stacks

Depending on your goal, you might want to take a different SARMs stack. If you’re trying to bulk up, for example, add some RAD 140 to the mix.

While your dosage may depend on your goals, here’s what I’m currently taking to shred fat and build muscle:

According to the studies done, you could technically double the dosage and be safe. Most research supports that that’s the max dosage, though.

Bulking StackCutting Stack
50mg Ostarine25mg Ostarine
30mg RAD 14010mg Ligandrol
20mg Ligandrol10mg Cardarine

That being said, I’ve been on my cycle for almost a month now, and feel zero side effects. Absolutely no SARMs side effects at all.

I’m going to follow this protocol for 12 weeks, although you can also choose to do 8 weeks if you wish. Follow up with a PCT.

I’ve done steroids before, and let me tell you, SARMs are far better. They’ve given me great euphoria, incredible strength, and phenomenal endurance, and I have had NONE of the negative side effects that steroids gave me.


Bulking Stack

If you’re trying to bulk up, I recommend you take a cycle of RAD 140 and Ostarine, for 90 days straight. This will give you some serious mass.

Just take 50mg of Ostarine and 30mg of RAD 140 each day, for 90 days straight, and you’ll put on at least 25 pounds of muscle. No joke.


How to Take Ostarine

Taking Ostarine is quite simple. If you get it from Proven Peptides, which I highly recommend, you will be taking liquid.

Just put a full dropper in a glass of water, swish it around, and drink it. Pour some more water in there, and drink it up again, to get any last bits of Ostarine liquid that might be left over.

Do this first thing in the morning, on your on and off days, for the full length of your cycle. That’s it! Taking Ostarine is simple.


When to Take MK2866

Personally, I just take my Ostarine first thing in the morning. Some people freak out over when to take it, but it doesn’t matter too much.

Since Ostarine has a half life of 24 hours, there will be a lot of it in your system regardless of when you take it.

Personally, I take Ostarine first thing in the morning on an empty stomach, with a pre workout like GAT Nitraflex, before I smash the gym.

Take it every day, on both your on days and your off days, for the full length of your cycle. I recommend a cycle of 8-12 weeks, and then a PCT.


Best MK 2866 PCT

red pct post cycle therapy

My favorite PCT for Ostarine

Even though I haven’t experienced any side effects while taking Ostarine, some people still claim that it shuts down your HPG Axis.

In other words, while evidence shows us that SARMs such as Ostarine have very few (if any) side effects, it’s still best to err on the side of caution.

For “PCT” or Post Cycle Therapy, nothing major is needed. The idea behind PCT is that it gets your testosterone levels back to normal.

Again, nothing major is needed here—just one bottle of Red PCT.


Running Post Cycle Therapy

A lot of guys think you need Nolvadex or Clomid for your Ostarine PCT, but in my experience this is only necessary if you’re taking steroids.

Because SARMs such as MK-2866 are much easier on your system, all you need is a simple testosterone boosting PCT to recover afterwards.

My favorite PCT for Ostarine is called Red PCT 2.0, and after checking my blood results before and after cycle, it’s safe to say that it works.

Here’s what Red PCT 2.0 contains:

  • Chlorophytum Borivilianum (Boosts Testosterone)
  • N-Acetyl L-Cysteine (Powerful Liver Detoxification)
  • Diindolymethane (Reduces Estrogen Levels)

In layman’s terms, all of these ingredients work synergistically to detoxify your body, preserve your muscle gains, and shoot your testosterone up.

All you need is one bottle—nothing more, nothing less. It will last you for about a month, which is exactly what you need.

Just start taking it after you’ve run out of SARMs, and give your body a break from the stuff. Take three capsules daily. One with breakfast, one with lunch, and one with dinner, and you’re good to go.


Where to Buy Ostarine

proven peptides banner ad

As someone who’s been using supplements for nearly a decade now, let me tell you there’s a LOT of bullshit out there. Especially with SARMs.

So when it comes to stuff like this, you want to be 100% certain that what you’re getting is completely unadulterated, 100% pure SARMs.

That’s just what I’m going to give you. For all of your SARMs needs online, I recommend you go through Proven Peptides.

They’re a US-based pharmacy that has an independent, third party lab verify EVERYTHING. So you know their SARMs are 100% pure.

If you want to know more, I recommend you read my full Proven Peptides Review. It’s got all the nitty gritty details about buying SARMs.

Trust me when I say that buying SARMs online is like wading through a swamp filled with con artists, crooks, and flat out liars. Proven Peptides is none of these things—their shit is 100% the real deal.

Better yet, if you click on this link and use the code “Masculinedev” you’ll get 10% off, plus free shipping on any of your orders over $75.

They’ve also got a phenomenal customer support section, which includes both email AND a telephone number. So whether you want to buy just Ostarine, or the whole meal deal, you can rest easy.


The Final Verdict

ostarine for sale

The bottom line is that Ostarine is an incredibly powerful muscle-building supplement that should NOT be abused.

When used properly, Ostarine can be an extremely powerful weapon in your bodybuilding arsenal. Within a matter of weeks, you can put on pounds and pounds of lean, dense muscle.

When you do decide to take Ostarine, I recommend that you take it with the other SARMs that I mentioned.

Stacking Ostarine with Ligandrol and Cardarine is bar-none the best way to build a lean, shredded physique within a fraction of the time it’d normally take. Do it and trust me, you won’t be disappointed.

If you do decide to take Ostarine, I recommend you do one of my best workout routines for men, in combination with it.

Taking SARMs alone will give you crazy results… but if you take them while also doing great workout routine? You’ll look like Thor in no time.

Frequently Asked Questions
❓ What is Ostarine?

Ostarine is a potent selective androgen receptor modulator, or SARM for short, which has been clinically proven to build muscle and shred fat. MK 2866 has also been clinically proven to have minimal side effects, unlike anabolic steroids.

❓ How Does Ostarine Work?

Ostarine works by binding to androgen receptors in your skeletal tissue, while avoiding androgen receptors in your organs. This means that using a SARM like MK-2866, users can expect to build large amounts of muscle, with minimal side effects.

❓ What Does Ostarine Do?

Shortly after ingestion, Ostarine (MK-2866) binds to androgen receptors in the bicep, tricep, back, chest, and leg muscles in the body. This signals them to build more muscle and increase protein synthesis.

In other words, according to most clinical studies, even a moderate dose of Ostarine (such as 25mg/day) can drastically increase muscle mass, reduce fat, and increase strength in users.

❓ What's The Best Ostarine Cycle?

Depending on your goals, the best Ostarine cycle will change. If you're trying to bulk up, taking Ostarine with RAD 140 is a great place to start. If you want to lose weight, taking Ostarine with Ligandrol and Cardarine is another cycle you can try.

❓ What's The Best Ostarine Dosage?

Studies have shown that Ostarine (MK 2866) is safe in dosages up to 50mg, however most users take less than this. If you're a beginner, it's recommended that you start with an Ostarine dose of 25mg/day and assess your tolerance.

❓ How Long Does Ostarine Stay in Your System?

Ostarine, otherwise known as MK 2866, has a half life of 24 hours, which means that after one day, 50% of it will be out of your system. Within two days, 25% of it will be out of your system, and within a week, it will all be completely out of your body.

About the Author Jon Anthony

Jon Anthony is a dating coach, fitness expert, and self-improvement guru. He dropped out of college to start Masculine Development in 2015, and has since been self-employed, helping men across the world achieve their best lives. You can best reach him on social media, or via email for questions.

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